张有来 简介

姓名

张有来

性别

男

出生年月

1982.11

学历学位

博士

职称

讲师

系别

制药工程系

导师类型

电话

13752321204

Email

youlai@tjut.edu.cn

办公/

科研室

19号楼411室

所属学科

研究

方向

1. 新型荧光探针的设计合成及性质研究

2. 新型光敏保护基的设计合成及应用研究

3. 光控释药模型体系的设计合成及性能研究

讲授课程： 药事管理 金属有机化学

主要科研项目及代表性成果(包括鉴定项目、论文、专著、获奖、专利等)：

1.国家自然青年科学基金项目(No.21303120) 新型靶向输送-光控释放抗癌前药模型的设计合成及荧光成像研究(2014/1-2016/12); 25万 张有来 第一  

2.天津市自然科学基金 (No.13JCYBJC42100) 新型光控保护基在多肽合成及智能释药中的应用研究(2013/10-2016/9);10万 张有来 第一  

3.天津市“131” 创新型人才培养工程第三层次(2013/10-2015/9);3万张有来  

4.天津市高等学校国家级大学生创新创业训练计划项目(No.201410060024) (2014/6-2016/6); 2万 指导教师 张有来  

论文:

1、Youlai  Zhang,  Hiroki Tanimoto, Yasuhiro Nishiyama, Tsumoru Morimoto, Kiyomi Kakiuchi^*,  Novel Photolabile Protecting Group for Phosphate Compounds Synlett, 2012,  23, 367-370.

2、Youlai  Zhang,  Ryo Sugiura, Hiroki Tanimoto, Yasuhiro Nishiyama,  Tsumoru  Morimoto, Kiyomi  Kakiuchi^*,Synthesis  of New Thiochromone-type Photolabile Protecting Group and Application to  Various Acids, The 92^th Conference of  Japanese Chemical Society, Yokohama, Abstract book  IV, 2012,2K2-27  p.1616.

3、Youlai  Zhang,  Hiroki Tanimoto, Yasuhiro Nishiyama, Tsumoru Morimoto, Kiyomi  Kakiuchi^*,Synthesis  of Hetarenoindanone  Based on Selenium Dioxide-Promoted Direct Intramolecular Cyclization, Heterocycles,2011,  83 (10), 2237-2342.

4、Youlai  Zhang,  Ryo Sugiura, Hiroki Tanimoto, Yasuhiro  Nishiyama, Tsumoru  Morimoto, Kiyomi  Kakiuchi^*, Synthesis of  New Photolabile Protecting Group and Application to Phosphate Derivatives, The  55^th Symposium on the Chemistry of Terpenes, Essential Oils, and  Aromatics (TEAC), Ibaraki, Abstract book2AII-5, 2011, p.290-292.

5、Youlai  Zhang,  Hiroki  Tanimoto, Yasuhiro  Nishiyama, Tsumoru  Morimoto, Kiyomi  Kakiuchi^*, Synthesis of  New Thiochromone-type Photolabile Protecting Group Having Diazomethyl Group  and Application to Phosphate Derivatives, The  91^th Conference of Japanese Chemical Society, Yokohama, Abstract  bookIV, 2C5-41, 2011, p.1333.

6、Yingjie  Lei^*, Jie Ouyang^*, Youlai Zhang,  Mei Ding, Synthesis and Spectral Characterization of Novel  Sulfhydryl-reactive Benzimidazole Fluorescent Probes, Chem. Res. Chinese  U.2010,26(2),  402-405.

7、Yingjie  Lei^*, Jie Ouyang^*, Youlai Zhang,  Mei Ding,Synthesis  of 2-(1H-Benzo[d]imidazol-2- yl)phenyl Phosphate asa  Fluorescent Probe for Determination of ALP,Chin.J.Chem. 2009,27, 2413-2417.

8、Youlai.  Zhang,  Yoshinori Gosho, Satoru Kitani, Ken. Tsutsumi, Tsumoru Morimoto, Kiyomi  Kakiuchi^*, Synthesis and Applications of  Thiochromone S,S-Dioxides as New Photolabile ProtectingGroups,  The Eleventh International Kyoto Conference on New Aspects of Organic  Chemistry (IKCOC-11), Kyoto, November 9-13, PB-163, Abstract book II, 2009,  p.218.

9、Youlai  Zhang,  Synthesis  and Photo-physical Properties of Novel –SH Fluorescent Probes,  The 31^st Conference of Japanese Photochemistry. Kyoto, Abstract  book, 2009, p.62.

10、Yingjie  Lei^*,  Hongqin Shen, Youlai Zhang, Jie  Ouyang,Synthesis  and photo-physical properties of substituted 2-(2-Hydroxyphenyl)- benzimidazoles, Chem.  J. Int.  2008,10  (4),  105026.

获奖:

1、日本化学会优秀演讲奖（2012年日本化学会92届年会），Synthesis of New Thiochromone-type  Photolabile Protecting Group and Application to Various Acids，第一。