王亮简介

姓名

王亮

性别

男

出生年月

1979.04

学历学位

博士

职称

副教授

系别

制药系

导师类型

硕导

电话

15122310256

Email

wangliang@tjut.edu.cn 或 19738097@qq.com

办公/

科研室

19号楼413室

所属学科

081704 应用化学/ /100701 药物化学

研究

方向

1.生物医用磁性纳米材料

2.智能荧光高分子

3.生物可降解聚酯

讲授课程：

主要科研项目及代表性成果(包括鉴定项目、论文、专著、获奖、专利等)：

项目:

1.国家自然科学基金项目：树型聚酯/聚缩水甘油醚嵌段共聚物多功能靶向纳米材料（51143003）2012.1-2012.12，10万，主持

2..国家自然科学基金项目：可点击树型共聚物的分子设计及其复合功能纳米载体的肿瘤靶向性能研究  （51203116）2013.1-2015.12，25万，主持

2.天津市自然科学基金：树型聚酯/聚缩水甘油醚嵌段共聚物多功能靶向纳米材料（12JCQNJC02000），2012.5-2015.4，8万，主持

3. 天津市高等学校科技发展基金计划项目：两亲性树型共聚物的分子设计及其多功能靶向药物载体的构建（20110501），2011.11-2014.10，4万，主持

论文:

1.Liang Wang,  K. G. Neoh, E. T. Kang andd Borys Shuter. Multifunctional  polyglycerol-grafted Fe₃O₄@SiO₂  nanoparticles for targeting ovarian cancer cells, Biomaterials 2011,  32(8):2166-2173. (IF=7.88)

2.Liang Wang,  Liqun Xu, Koon Gee Neoh and En-Tang Kang. Water-soluble  Highly Fluorescent Poly[poly(ethylene glycol) methyl ether methacrylate] for  Cell Labeling. Journal of Materials Chemistry 2011, 21 (18):6502-6505  (IF=4.79)

3.Liang Wang,  K. G. Neoh, E. T. Kang, Borys Shuter and Shi-Chang Wang. Biodegradable  Magnetic-Fluorescent Magnetite/Poly(DL-lactic acid-co-α,β-malic acid)  Composite Nanoparticles for Stem Cell Labeling, Biomaterials 2010,  31(13):3502-3511. (IF=7.88)

4.Liang Wang,  K. G. Neoh, E. T. Kang, Borys Shuter and Shih-Chang Wang. Superparamagnetic  hyperbranched polyglycerol-grafted Fe₃O₄ nanoparticles  as a novel magnetic resonance imaging contrast agent: an in vitro assessment.  Advanced functional materials 2009, 19(16):2615-2622. (IF=8.51)

5.Liang Wang, Xiaohua Jia, Yongsheng Chen, Yongzhe Che,  Zhi Yuan.  Synthesis, degradability and cell affinity of poly(DL-lactide-co-RS-hydroxyethyl-β-malolactonate).  Journal of Biomedical Materials Research：Part A 2008, 87A(2):459-469.  (IF=3.04)

6.Liang Wang,  Xiaohua Jia, Zhi Yuan. Synthesis and  characterization of novel functionalized polylactides with pendent hydroxyl  arms. Polymer 2006, 47(20):6978-6985. (IF=3.83)

7.Liang Wang,  Xiaohua Jia, Zhi Yuan. Synthesis and  Characterization of a functionalized amphiphilic diblock copolymer:  MePEG-b-poly(DL-lactide-co- RS-β-malic acid). Colloid and  Polymer Science 2006, 285(3):273-281. (IF=2.44)

8.Liang Wang, Xiaohua  Jia, Zhi Yuan. Synthesis and characterization of  4-(2-Benzyloxyethoxycarbonyl)-2-oxetanone. Chemical Journal of Chinese  Universities 2005, 26(9):1650-1652. (IF=0.66)

9.Liqun Xu, Liang Wang, Bin  Zhang, Chee Hong Lim, Yu Chen, Koon-Gee Neoh, En-Tang Kang and GuoDong Fu. Functionalization  of Reduced Graphene Oxide Nanosheets via Stacking Interactions with the  Fluorescent and Water-soluble Perylene Bisimide-Containing Polymers. Polymer  2011, 52(11):2376-2383. (IF=3.83, co-first author)

10.Xiaohui Li, Liang  Wang, Jing Yang, CunXian Song. Synthesis  and characterization of amphiphilic poly (epsilon-caprolactone)-b-  hyperbranched polyglycidol. Chemical Journal of Chinese Universities  2008, 29 (10):2107-2110. (IF=0.66)

11.Min Li, LiQun Xu, Liang Wang,  Y. P. Wu, Jun Li, Koon-Gee Neoh and En-Tang Kang. Clickable  Poly(ester amine) Dendrimer-grafted Fe₃O₄ Nanoparticles  Prepared via Successive Michael Addition and Alkyne-Azide Click Chemistry. Polymer  Chemistry 2011, 2(6):1312-1321.

12.Chao Huang, Koon Gee Neoh, Liang  Wang, En-Tang Kang and Borys Shuter. Surface  functionalization of superparamagnetic nanoparticles for the development of  highly efficient magnetic resonance probe for macrophages. Contrast  Media & Molecular Imaging 2011,  6(4):298-307 (IF=4.02).

13.Chao Huang, Koon Gee Neoh, Liang  Wang, En-Tang Kang and Borys Shuter. Magnetic  nanoparticles for magnetic resonance imaging: modulation of macrophage uptake  by controlled PEGylation of the surface coating. Journal of Materials  Chemistry 2010, 20(39): 8512–8520. (IF=4.79)

14.Guoliang Li, Dawn Liming Zeng, Liang  Wang, Baoyu Zong, K. G. Neoh and E. T. Kang. Hairy  Hybrid Nanoparticles of Magnetic Core, Fluorescent Silica Shell, and  Functional Polymer Brushes. Macromolecules  2009, 42(21):8561-8565. (IF=4.84)

15.Wei  Wang, Yuan Liu, Jun Wang, Xiaohua Jia, Liang Wang, Yuan, Zhi, et al. A  Novel Copolymer Poly(Lactide-co-beta-Malic Acid) with Extended Carboxyl Arms  Offering Better Cell Affinity and Hemacompatibility for Blood Vessel  Engineering. Tissue Engineering Part A2009, 15(1):65-73.

16.Wei Wang, Xiaohua Jia, Yuan Liu, Liang  Wang, Zhi Yuan, et al. Preparation of  Functionalized PLA with Pendant Carboxyl and its blood compatibility and cell  adhesion. Chemical Journal of Chinese Universities 2008, 29:1-4.  (IF=0.66)

17.Wei Wang, Xiaohua Jia, Yuan Liu, Liang  Wang, Zhi Yuan. Synthesis and  platelet adhesion capacities study of functionalized polylactides with  pendant carboxyl arms. Acta Polymerica Sinica 2008, 2:97-101.

18.Liang Wang,  Xiaohui Li, Cuxian Song. Poly  (epsilon-caprolactone)-Polyglycidol Hyperbranched Conjugates. The 35th  Annual Meeting & Exposition of the Controlled Release Society (New York U.S., 2008). (会议论文)

专利：

1.端胺基星型聚乙丙交酯/聚乙二醇嵌段共聚物、制备方法、载药纳米胶束及应用（专利号：ZL200710058430.9，完成人：王亮，宋存先）